Open AccessComparison of conventional Ziehl–Neelsen method of acid fast bacilli with modified bleach method in tuberculous lymphadenitis
Author(s) -
Murli Krishna,
Sheetal G. Gole
Publication year - 2017
Publication title -
journal of cytology/journal of cytology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.267
H-Index - 19
eISSN - 0974-5165
pISSN - 0970-9371
DOI - 10.4103/joc.joc_84_16
Subject(s) - medicine , caseous necrosis , langhans giant cell , ziehl–neelsen stain , tuberculous lymphadenitis , tuberculosis , bleach , acid fast , mycobacterium tuberculosis , bacilli , pathology , giant cell , lymph node , sputum , bacteria , biology , chemistry , organic chemistry , genetics
Tuberculosis caused by Mycobacterium tuberculosis is a chronic infectious disease and a major health problem in developing countries, with lymphadenopathy being the most common presentation. Tuberculous lymphadenitis can be diagnosed on fine needle aspiration cytology of lymph node. Conventional Ziehl-Neelsen method for acid fast bacilli plays a key role in the diagnosis and monitoring of treatment for tuberculosis, however, with low sensitivity. Present study emphasizes the role of bleach concentration method in fine needle aspiration cytology of lymph nodes over conventional direct smear microscopy.