Open AccessA comparative study of cell block versus biopsy for detection of epidermal growth factor receptor mutations and anaplastic lymphoma kinase rearrangement in adenocarcinoma lung
Author(s) -
Vani Gupta,
Saumya Shukla,
Nuzhat Husain,
Surya Kant,
Rajiv Garg
Publication year - 2019
Publication title -
journal of cytology/journal of cytology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.267
H-Index - 19
eISSN - 0974-5165
pISSN - 0970-9371
DOI - 10.4103/joc.joc_66_18
Subject(s) - anaplastic lymphoma kinase , epidermal growth factor receptor , medicine , immunohistochemistry , lung cancer , pathology , large cell , adenocarcinoma , immunocytochemistry , biopsy , cancer research , anaplastic large cell lymphoma , lymphoma , cancer , malignant pleural effusion
Lung cancer is a leading cause of deaths attributed to cancer worldwide. Epidermal growth factor receptor (EGFR) mutation and anaplastic lymphoma kinase (ALK) rearrangement are commonly found in patients of adenocarcinoma lung against, which targeted therapy is available. In this era of personalized medicine, it is a rationale to detect these molecular alterations in cases of lung carcinomas.