Open AccessCytological diagnosis of Rosai–Dorfman disease: A study of twelve cases with emphasis on diagnostic challenges
Author(s) -
Rallapalli Rajyalakshmi,
Muhammad Naseem Akhtar,
Swathi Yarlagadda,
Ranjani Chakravarthi,
Jeeru Bhaskara Reddy,
Maddirala Beulah Priscilla
Publication year - 2020
Publication title -
journal of cytology/journal of cytology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.267
H-Index - 19
eISSN - 0974-5165
pISSN - 0970-9371
DOI - 10.4103/joc.joc_4_19
Subject(s) - medicine , emphasis (telecommunications) , rosai–dorfman disease , disease , pathology , dermatology , electrical engineering , engineering
Rosai-Dorfman disease, also known as Sinus histiocytosis with massive lymphadenopathy, is a benign proliferative disorder of histiocytes. It typically affects lymph nodes; however, extranodal disease is being increasingly reported. The latter entity poses exceptional diagnostic challenge clinico-radiologically by forming mass lesions. Fine needle aspiration cytology (FNAC) is the investigation of choice to avoid unnecessary surgery as the majority are self-limiting.