Evaluation of p16/Ki-67 dual staining compared with HPV genotyping in anal cytology with diagnosis of ASC-US for detection of high-grade anal intraepithelial lesions | Zendy

Maxime Pichon | Zendy; Marie Joly | Zendy; Frédérique Lebreton | Zendy; M Benchaib | Zendy; Yahia Mekki | Zendy; Mojgan DevouassouxShisheboran | Zendy

Open Access

Evaluation of p16/Ki-67 dual staining compared with HPV genotyping in anal cytology with diagnosis of ASC-US for detection of high-grade anal intraepithelial lesions

Author(s) -

Maxime Pichon,

Marie Joly,

Frédérique Lebreton,

M Benchaib,

Yahia Mekki,

Mojgan DevouassouxShisheboran

Publication year - 2019

Publication title -

journal of cytology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.267

H-Index - 19

eISSN - 0974-5165

pISSN - 0970-9371

DOI - 10.4103/joc.joc_131_18

Subject(s) - squamous intraepithelial lesion , cytology , genotyping , anal cancer , medicine , hpv infection , biopsy , staining , pathology , cervical cancer , cancer , genotype , cervical intraepithelial neoplasia , biology , biochemistry , gene

Human Papillomavirus (HPV) infection is the main risk factor for anogenital cancer. The objective of this study was to compare p16/Ki-67 dual staining to HPV genotyping in anal cytology samples with an atypical squamous cell of undetermined significance (ASC-US) for the identification of high-grade squamous intraepithelial lesion (HSIL).

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