Open AccessCytomorphological features of lung adenocarcinoma with anaplastic lymphoma kinase gene rearrangement
Author(s) -
Nuzhat Husain,
Saumya Shukla,
Anurag Gupta,
Nidhi Anand
Publication year - 2019
Publication title -
journal of cytology/journal of cytology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.267
H-Index - 19
eISSN - 0974-5165
pISSN - 0970-9371
DOI - 10.4103/joc.joc_127_18
Subject(s) - anaplastic lymphoma kinase , medicine , crizotinib , pathology , adenocarcinoma , histopathology , gene rearrangement , anaplastic large cell lymphoma , lung cancer , lymphoma , pleomorphism (cytology) , signet ring cell , pathological , immunohistochemistry , cancer , gene , biology , biochemistry , malignant pleural effusion
The anaplastic lymphoma kinase (ALK) gene rearrangement is a predictive and prognostic marker in pulmonary adenocarcinoma. A series of clinical and pathological features have been documented in patients who harbor this translocation.