Open AccessDecrease in heart rate following the administration of sugammadex in adults
Author(s) -
Trent Sims,
Joshua Peterson,
Mohammed Hakim,
Catherine Roth,
Dmitry Tumin,
Joseph D. Tobias,
Jennifer Hansen
Publication year - 2020
Publication title -
journal of anaesthesiology-clinical pharmacology/journal of anaesthesiology clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.466
H-Index - 32
eISSN - 2231-2730
pISSN - 0970-9185
DOI - 10.4103/joacp.joacp_346_19
Subject(s) - medicine , bradycardia , sugammadex , anesthesia , heart rate , prospective cohort study , blood pressure , rocuronium , surgery , propofol
Sugammadex is a novel agent for reversal of steroidal neuromuscular blocking agents (NMBAs) with potential advantages over acetylcholinesterase inhibitors. In preclinical trials, there have been rare instances of bradycardia with progression to cardiac arrest. To better define this issue, its incidence and mitigating factors, we prospectively evaluated the incidence of bradycardia after sugammadex administration in adults.