Open AccessAssociation between intravenous acetaminophen and reduction in intraoperative opioid consumption during transsphenoidal surgery for pituitary tumors
Author(s) -
Upasana Banerjee,
Katherine Hagan,
Shreyas Bhavsar,
Roxana Grasu,
Anh Dang,
Ian E. McCutcheon,
Miguel Suárez,
Vijaya Gottumukkala,
Juan P. Cata
Publication year - 2018
Publication title -
journal of anaesthesiology-clinical pharmacology/journal of anaesthesiology clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.466
H-Index - 32
eISSN - 2231-2730
pISSN - 0970-9185
DOI - 10.4103/joacp.joacp_276_17
Subject(s) - medicine , acetaminophen , anesthesia , fentanyl , opioid , sedation , transsphenoidal surgery , nausea , vomiting , surgery , pituitary adenoma , adenoma , receptor
Pain during and after transsphenoidal surgeries originates from stimulation of branches of the trigeminal cranial nerve that supply the inner aspect of the nose cavity and dura mater. Thereby, patients undergoing transsphenoidal surgery may require moderate-to-large amounts of analgesics including opioids. Intravenous acetaminophen provides analgesia and reduces opioid consumption for a wide variety of surgeries. We hypothesized that the use of intravenous acetaminophen is associated with a reduction in intraoperative opioid consumption and provides significant analgesia during and after transsphenoidal surgery.