Open AccessEfficacy of ondansetron and palonosetron in prevention of shivering under spinal anesthesia: A prospective randomized double-blind study in patients undergoing elective LSCS
Author(s) -
Manoj K. Sharma,
Deepak Mishra,
Nitin Goel
Publication year - 2021
Publication title -
journal of anaesthesiology-clinical pharmacology/journal of anaesthesiology clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.466
H-Index - 32
eISSN - 2231-2730
pISSN - 0970-9185
DOI - 10.4103/joacp.joacp_215_18
Subject(s) - medicine , ondansetron , palonosetron , anesthesia , shivering , antiemetic , randomized controlled trial , spinal anesthesia , vomiting , surgery
Postanesthesia shivering (PAS) is a common, distressing experience. Ondansetron, the classical 5HT 3 antagonist has been in use for its prevention since long. Palonosetron, a newly introduced potent antiemetic drug with better pharmacodynamics is currently in use by clinicians. Hence, a study was conducted to compare the efficacy of ondansetron and palonosetron in preventing PAS in patients undergoing elective lower segment caesarean section (LSCS) under spinal anaesthesia.