
Effect of lactate versus acetate-based intravenous fluids on acid-base balance in patients undergoing free flap reconstructive surgeries
Author(s) -
Sunil Rajan,
Soumya Srikumar,
Pulak Tosh,
Lakshmi Kumar
Publication year - 2017
Publication title -
journal of anaesthesiology-clinical pharmacology/journal of anaesthesiology clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.466
H-Index - 32
eISSN - 2231-2730
pISSN - 0970-9185
DOI - 10.4103/joacp.joacp_18_17
Subject(s) - medicine , sodium bicarbonate , anesthesia , randomized controlled trial , acidosis , bicarbonate , blood lactate , acid–base homeostasis , base excess , surgery , blood pressure , heart rate , chemistry
Use of lactated intravenous fluids during long surgeries could cause lactate accumulation and lactic acidosis. Acetate-based solutions could be advantageous as they are devoid of lactate. The primary aim of the study was to assess the effect of use of an acetated solution or Ringer's lactate (RL) as intraoperative fluid on lactate levels in patients without hepatic dysfunction undergoing prolonged surgeries.