Open AccessEffect of dexmedetomidine on intracranial pressures during laparoscopic surgery: A randomized, placebo-controlled trial
Author(s) -
Nishant Sahay,
Umesh Kumar Bhadani,
Subhajit Guha,
Alok Himanshu,
Chandni Sinha,
Mamta Bara,
Anubha Sahay,
Alok Ranjan,
Parminder Singh
Publication year - 2018
Publication title -
journal of anaesthesiology-clinical pharmacology/journal of anaesthesiology clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.466
H-Index - 32
eISSN - 2231-2730
pISSN - 0970-9185
DOI - 10.4103/joacp.joacp_171_17
Subject(s) - dexmedetomidine , medicine , pneumoperitoneum , trendelenburg position , anesthesia , laparoscopic surgery , placebo , laparoscopy , randomized controlled trial , saline , loading dose , surgery , sedation , alternative medicine , pathology
Laparoscopic surgeries cause an increase in intracranial pressure (ICP) after creation of pneumoperitoneum. Sonographically measured, optic nerve sheath diameter (ONSD) correlates well with changes in ICP. Dexmedetomidine (Dex), an α 2 agonist is extensively used in day-care surgeries, although its effect on ICP during laparoscopy in humans has not been reported in the literature. The aim of this study was to note the effect of dexmedetomidine infusion on changes in ICPs during laparoscopic cholecystectomy.