Open AccessSingle intravenous bolus versus perioperative continuous infusion of tranexamic acid to reduce blood loss in abdominal oncosurgical procedures: A prospective randomized double-blind clinical study
Author(s) -
Ramakrishna Prasad,
Abhiruchi Patki,
Shibany Padhy,
R. Gopinath
Publication year - 2018
Publication title -
journal of anaesthesiology-clinical pharmacology/journal of anaesthesiology clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.466
H-Index - 32
eISSN - 2231-2730
pISSN - 0970-9185
DOI - 10.4103/joacp.joacp_122_17
Subject(s) - tranexamic acid , medicine , anesthesia , bolus (digestion) , perioperative , hematocrit , saline , blood transfusion , surgery , post hoc analysis , blood loss
Intraoperative use of a single bolus dose of tranexamic acid may not be sufficient to prevent bleeding in the early postoperative period. The present study was carried out to compare the effect of two dose regimens of tranexamic acid in reducing perioperative blood loss and the amount of allogenic blood transfusion in abdominal tumor surgery.