Open AccessA prospective, randomized, open-label study comparing the efficacy and safety of clonazepam versus nortriptyline on quality of life in 40+ years old women presenting with restless leg syndrome
Author(s) -
Roshi,
Vishal R Tandon,
Annil Mahajan,
Sudhaa Sharma,
Vijay Khajuria
Publication year - 2018
Publication title -
journal of mid-life health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.423
H-Index - 11
eISSN - 0976-7819
pISSN - 0976-7800
DOI - 10.4103/jmh.jmh_25_18
Subject(s) - nortriptyline , clonazepam , medicine , quality of life (healthcare) , prospective cohort study , randomized controlled trial , antidepressant , physical therapy , psychiatry , amitriptyline , nursing , anxiety
Restless legs syndrome (RLS) is a neurological disorder characterized by an urge to move the legs usually accompanied by unpleasant leg sensations. RLS also impacts health related quality of life (QOL) in patients suffering from it. Further, it affects women more than men. Although a voluminous literature of studies is available evaluating the role of benzodiazepines (clonazepam and antidepressant (nortriptyline) in the treatment of RLS, but to the best of our knowledge, no comparative study is available comparing both of these drugs for efficacy and safety for the treatment of RLS QoL among 40 + years old women.