Open AccessSecretory endometrial adenocarcinoma: A rare sequelae in a postmenopausal woman following tamoxifen therapy for breast cancer
Author(s) -
Sonam Sharma
Publication year - 2020
Publication title -
journal of mid-life health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.423
H-Index - 11
eISSN - 0976-7819
pISSN - 0976-7800
DOI - 10.4103/jmh.jmh_104_19
Subject(s) - tamoxifen , medicine , breast cancer , endometrial cancer , hormonal therapy , oncology , gynecology , differential diagnosis , cancer , pathology
The double-edged sword effect of tamoxifen therapy on the female reproductive system including the breast is quite well established. However, it is still poorly understood at the molecular level which significantly affects the management of such patients receiving it in terms of therapeutics and prognosis. An experience of an extremely rare case of secretory endometrial adenocarcinoma developing due to the adverse effect of tamoxifen used for the treatment of breast cancer in a 60-year-old woman is being described herewith so as to create awareness among the dealing clinicians about the occurrence of rare histological types of endometrial cancer after long-term tamoxifen therapy. The approach to such a case, pathogenesis, differential diagnosis, and a brief literature review is also presented.