Open AccessHistopathological study with immunohistochemical expression of vascular endothelial growth factor in placentas of hyperglycemic and diabetic women
Author(s) -
D. Bhattacharjee,
Santosh Kumar Mondal,
Pratima Garain,
Palash Mandal,
Rudra Ray,
Goutam Dey
Publication year - 2017
Publication title -
journal of laboratory physicians
Language(s) - English
Resource type - Journals
eISSN - 0974-7826
pISSN - 0974-2727
DOI - 10.4103/jlp.jlp_148_16
Subject(s) - syncytiotrophoblast , placenta , diabetes mellitus , medicine , vascular endothelial growth factor , immunohistochemistry , gestational diabetes , fibrinoid necrosis , pathogenesis , pathology , hyperplasia , endocrinology , pregnancy , fetus , biology , gestation , vegf receptors , disease , genetics , vasculitis
Spectrum of hyperglycemia in pregnancy includes gestational diabetes mellitus (GDM), mild hyperglycemia, and overt diabetes. Many authors have worked on morphological changes of the placenta in diabetes, but few studies have correlated histopathological changes with vascular endothelial growth factor (VEGF) immunoexpression. The aim of this study was to detect different histopathological changes in various groups of diabetic placentas and to correlate with VEGF immunoexpression.