Open AccessCongenital insensitivity to pain in a 1-year-old boy
Author(s) -
MK Navya,
GV Pramod,
GP Sujatha,
L Ashok
Publication year - 2019
Publication title -
journal of the indian society of pedodontics and preventive dentistry/journal of indian society of pedodontics and preventive dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.378
H-Index - 33
eISSN - 1998-3905
pISSN - 0970-4388
DOI - 10.4103/jisppd.jisppd_340_18
Subject(s) - pain sensation , sensation , medicine , affect (linguistics) , pediatrics , psychology , anesthesia , neuroscience , communication
Congenital insensitivity to pain (CIP) is a rare autosomal recessive genetic condition which causes reduced pain sensation, thermal sensation, and habit of self-mutilation. It is a life-threatening condition where due to reduced pain sensation, patient might not understand the severity of the injury which can eventually lead to death. Such people live a compromised life and can also affect them psychologically. Here, we are reporting a case of an infant with clinical features suggestive of CIP with a mutation in exon 5 of PRDM12 gene. The child has minimal response to pain along with self-mutilation and mental retardation.