Open AccessHuman amnion membrane: Potential applications in oral and periodontal field
Author(s) -
Ranjana Mohan,
Aashima Bajaj,
Mohan Gundappa
Publication year - 2017
Publication title -
journal of international society of preventive and community dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.476
H-Index - 14
eISSN - 2250-1002
pISSN - 2231-0762
DOI - 10.4103/jispcd.jispcd_359_16
Subject(s) - amnion , fetal membrane , mesenchyme , medicine , fetus , regeneration (biology) , regenerative medicine , immunogenicity , pathology , biology , microbiology and biotechnology , mesenchymal stem cell , pregnancy , immunology , stem cell , placenta , antibody , genetics
Human amniotic membrane (HAM) is derived from the fetal membranes which consist of the inner amniotic membrane made of single layer of amnion cells fixed to collagen-rich mesenchyme attached to chorion. HAM has low immunogenicity, anti-inflammatory properties and their cells can be isolated without the sacrifice of human embryos. Amniotic membrane has biological properties which are important for the experimental and clinical applications in managing patients of various medical specialties. Abundant, natural and wonderful biomembrane not only protects the foetus but also has various clinical applications in the field of dermatology, ophthalmology, ENT surgery, orthopedics and dental surgery. As it is discarded post-partum it may be useful for regenerative medicine and cell therapy to treat damaged or diseased tissues.