Open AccessUse of platelet rich plasma in the management of periodontal intra-osseous defects: A clinical study
Author(s) -
Mohammad Jalaluddin,
Dhirendra Kumar Singh,
Ipsita Jayanti,
Prasad Kulkarni,
Mohamed Faizuddin,
Fouzia Tarannum
Publication year - 2017
Publication title -
journal of international society of preventive and community dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.476
H-Index - 14
eISSN - 2250-1002
pISSN - 2231-0762
DOI - 10.4103/jispcd.jispcd_28_17
Subject(s) - medicine , platelet rich plasma , periodontology , dental alveolus , dentistry , debridement (dental) , platelet , connective tissue , gingival inflammation , periodontal disease , pathology
Periodontal disease is characterized by the presence of gingival inflammation, periodontal pocket formation, loss of connective tissue attachment, and alveolar bone around the affected tooth. Alveolar bone support and attachment apparatus regeneration has been achieved through various processes and have given elusive results. An expedient and cost-effective approach to obtain autologous platelet-derived growth factor (PDGF) and transforming growth factor (TGF)-β is the use of platelet-rich plasma (PRP). PRP is obtained by sequestrating and concentrating platelets by gradient density centrifugation.