Expression of matrix metalloproteinase-9 in gingival tissue biopsy in patients with slowly/moderately and rapidly progressing periodontitis: An observational study | Zendy

Thamil Selvan Muthuraj | Zendy; Papita Ghosh | Zendy; Prasanta Bandyopadhyay | Zendy; Snehasikta Swarnakar | Zendy; Puja Sarkar | Zendy; Abinaya Varatharajan | Zendy

Open Access

Expression of matrix metalloproteinase-9 in gingival tissue biopsy in patients with slowly/moderately and rapidly progressing periodontitis: An observational study

Author(s) -

Thamil Selvan Muthuraj,

Papita Ghosh,

Prasanta Bandyopadhyay,

Snehasikta Swarnakar,

Puja Sarkar,

Abinaya Varatharajan

Publication year - 2021

Publication title -

journal of indian society of periodontology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.309

H-Index - 28

eISSN - 0975-1580

pISSN - 0972-124X

DOI - 10.4103/jisp.jisp_811_20

Subject(s) - periodontitis , matrix metalloproteinase , medicine , extracellular matrix , pathology , chemistry , biochemistry

Matrix metalloproteinases (MMPs) are a group of host-derived zinc-dependent enzymes which mediates the destruction of the extracellular matrix. In periodontitis, there is excess production of MMPs associated with periodontal tissue destruction. The aim of this study was to estimate the level MMP-9 in both active and latent form in gingival tissue (GT) samples collected from periodontitis patients with different rates of progression and compare it with healthy individuals.

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