Open AccessExpression of matrix metalloproteinase-9 in gingival tissue biopsy in patients with slowly/moderately and rapidly progressing periodontitis: An observational study
Author(s) -
Papita Ghosh,
Thamil Selvan Muthuraj,
Prasanta Bandyopadhyay,
Snehasikta Swarnakar,
Puja Sarkar,
Abinaya Varatharajan
Publication year - 2021
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/jisp.jisp_811_20
Subject(s) - periodontitis , matrix metalloproteinase , medicine , extracellular matrix , pathology , chemistry , biochemistry
Matrix metalloproteinases (MMPs) are a group of host-derived zinc-dependent enzymes which mediates the destruction of the extracellular matrix. In periodontitis, there is excess production of MMPs associated with periodontal tissue destruction. The aim of this study was to estimate the level MMP-9 in both active and latent form in gingival tissue (GT) samples collected from periodontitis patients with different rates of progression and compare it with healthy individuals.