Open AccessEffects of recombinant human bone morphogenetic protein-2 compared to other biomaterials in the treatment of intrabony defects in periodontitis patients: A systematic review
Author(s) -
Raghavendra S Medikeri,
Vinayak Venkoosa Meharwade,
Kumar Ankit
Publication year - 2019
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/jisp.jisp_748_18
Subject(s) - medicine , dentistry , bone morphogenetic protein , periodontitis , furcation defect , platelet rich fibrin , bone grafting , radiography , chronic periodontitis , debridement (dental) , cochrane library , orthodontics , surgery , fibrin , randomized controlled trial , molar , biochemistry , chemistry , immunology , gene
Bone morphogenetic proteins have a powerful osteoinductive capacity and have been used as a new adjunct to graft materials for bone regeneration. The objectives of this systematic review are to assess the amount of radiographic bone fill, clinical attachment level (CAL) gain, and reduction in pocket depth (PD) in patients with intrabony defects in periodontitis patients following the use of recombinant human bone morphogenetic protein-2 (rhBMP-2).