Open AccessFree haem levels in gingival crevicular fluid and their relationship to periodontal clinical parameters, smoking and subgingival microbial composition
Author(s) -
Shobha Krishna Subbaiah,
Vanitha Krishna Subbaiah,
Mahantesha Sharanappa,
Anirban Chatterjjee,
Sreedevi Maddipati
Publication year - 2022
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/jisp.jisp_477_20
Subject(s) - medicine , periodontitis , dentistry , biomarker , chronic periodontitis , bleeding on probing , gingival and periodontal pocket , porphyromonas gingivalis , gastroenterology , physiology , biology , biochemistry
Periodontitis caused by multifactorial polymicrobial infection results in a destructive inflammatory process and loss of tooth supporting tissues. Many putative bacterial virulence factors that cause host destruction are regulated by iron and haem. Therefore, this study investigated the free haem levels in the gingival crevicular fluid (GCF) at periodontitis sites in smokers and nonsmokers and their relationship to subgingival microbial composition.