Open AccessInterleukin-21 and its association with chronic periodontitis
Author(s) -
Rani Vilas Lokhande,
Jeevan G Ambekar,
Kishore Bhat,
Nilima N. Dongre
Publication year - 2019
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/jisp.jisp_410_18
Subject(s) - chronic periodontitis , medicine , periodontitis , saliva , pathogenesis , interquartile range , biomarker , interleukin , cytokine , gastroenterology , immunology , dentistry , biology , biochemistry
Interleukin-21 (IL-21) is a pleiotropic cytokine, well documented to contribute to the development of Th17 cells which have been shown to play an important role in the pathogenesis of periodontitis. Periodontal disease is a chronic infection of tooth-supporting tissue.