Open AccessSerotypes of Aggregatibacter actinomycetemcomitans in relation to periodontal status and assessment of leukotoxin in periodontal disease: A clinico-microbiological study
Author(s) -
Sudhakar Shuntikudege Suprith,
Swati Setty,
Kishore Bhat,
Srinath Thakur
Publication year - 2018
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/jisp.jisp_36_18
Subject(s) - serotype , aggregatibacter actinomycetemcomitans , medicine , microbiology and biotechnology , virulence , chronic periodontitis , periodontal disease , periodontitis , aggressive periodontitis , immunology , biology , porphyromonas gingivalis , gene , biochemistry
Aggregatibacter actinomycetemcomitans (A.a) serotypes may add some important information of the pathogenetic background of periodontal infections. A.a leukotoxin is an important virulence factor in the pathogenesis of periodontal disease and its rate of progression. When compared to minimally leukotoxic strains, variants of A.a highly leukotoxic strains produce 10-20 times more leukotoxin.