Open AccessRelevance of single-nucleotide polymorphism to the expression of resistin gene affecting serum and gingival crevicular fluid resistin levels in chronic periodontitis and type 2 diabetes mellitus: A randomized control clinical trial
Author(s) -
Pranita Avinash Rode,
Rajashri A Kolte,
Abhay Kolte,
Hemant J. Purohit,
Charu Ahuja
Publication year - 2019
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/jisp.jisp_361_18
Subject(s) - resistin , medicine , chronic periodontitis , single nucleotide polymorphism , periodontitis , type 2 diabetes mellitus , gastroenterology , snp , insulin resistance , diabetes mellitus , endocrinology , adipokine , gene , genotype , insulin , genetics , biology
The present study is aimed to investigate whether single-nucleotide polymorphism (SNP) of resistin gene (RETN) at -420 and +299 sites, is associated with resistin levels in serum and gingival crevicular fluid (GCF) in periodontally healthy, chronic periodontitis (CP) with and without type 2 diabetes mellitus (T2DM) patients.