Relevance of single-nucleotide polymorphism to the expression of resistin gene affecting serum and gingival crevicular fluid resistin levels in chronic periodontitis and type 2 diabetes mellitus: A randomized control clinical trial
Author(s) -
Rajashri A. Kolte,
P Rode,
Abhay Kolte,
HemantJyotiswarup Purohit,
CharuRam Ahuja
Publication year - 2019
Publication title -
journal of indian society of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/jisp.jisp_361_18
Subject(s) - resistin , medicine , chronic periodontitis , single nucleotide polymorphism , periodontitis , gastroenterology , snp , type 2 diabetes mellitus , adipokine , diabetes mellitus , insulin resistance , endocrinology , gene , genotype , genetics , insulin , biology
The present study is aimed to investigate whether single-nucleotide polymorphism (SNP) of resistin gene (RETN) at -420 and +299 sites, is associated with resistin levels in serum and gingival crevicular fluid (GCF) in periodontally healthy, chronic periodontitis (CP) with and without type 2 diabetes mellitus (T2DM) patients.
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