Open AccessComparative assessment of periodontal regeneration in periodontal intraosseous defects treated with PepGen P-15 unaided or in blend with platelet-rich fibrin: A clinical and high-resolution computed tomography scan-assisted volumetric analysis
Author(s) -
Jyotsna Goyal,
Surinder Sachdeva,
Sanjeev Kumar Salaria,
Nishu Vakil,
Amit Mittal
Publication year - 2020
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/jisp.jisp_351_19
Subject(s) - platelet rich fibrin , medicine , gingival margin , chronic periodontitis , bleeding on probing , fibrin , dentistry , dental alveolus , periodontitis , nuclear medicine , clinical attachment loss , regeneration (biology) , clinical significance , pathology , immunology , biology , microbiology and biotechnology
PepGen P-15, a xenograft, has proven its periodontal regenerative potential. Platelet-rich fibrin (PRF) is an autologous platelet concentrate which too contributes to periodontal redevelopment through the release of different polypeptide progression factors. The present study intended to evaluate the regenerative potential of PepGen P-15 xenograft when used unaccompanied or in blend with PRF in periodontal intraosseous defects in humans through clinical and a novel computed tomography (CT) scan analysis technique.