Comparative assessment of periodontal regeneration in periodontal intraosseous defects treated with PepGen P-15 unaided or in blend with platelet-rich fibrin: A clinical and high-resolution computed tomography scan-assisted volumetric analysis | Zendy

Jyotsna Goyal | Zendy; Surinder Sachdeva | Zendy; SanjeevKumar Salaria | Zendy; Nishu Vakil | Zendy; Amit Mittal | Zendy

Open Access

Comparative assessment of periodontal regeneration in periodontal intraosseous defects treated with PepGen P-15 unaided or in blend with platelet-rich fibrin: A clinical and high-resolution computed tomography scan-assisted volumetric analysis

Author(s) -

Jyotsna Goyal,

Surinder Sachdeva,

SanjeevKumar Salaria,

Nishu Vakil,

Amit Mittal

Publication year - 2020

Publication title -

journal of indian society of periodontology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.309

H-Index - 28

eISSN - 0975-1580

pISSN - 0972-124X

DOI - 10.4103/jisp.jisp_351_19

Subject(s) - platelet rich fibrin , medicine , chronic periodontitis , gingival margin , fibrin , bleeding on probing , dentistry , periodontitis , nuclear medicine , dental alveolus , clinical attachment loss , gingival and periodontal pocket , regeneration (biology) , biology , microbiology and biotechnology , immunology

PepGen P-15, a xenograft, has proven its periodontal regenerative potential. Platelet-rich fibrin (PRF) is an autologous platelet concentrate which too contributes to periodontal redevelopment through the release of different polypeptide progression factors. The present study intended to evaluate the regenerative potential of PepGen P-15 xenograft when used unaccompanied or in blend with PRF in periodontal intraosseous defects in humans through clinical and a novel computed tomography (CT) scan analysis technique.

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