Open AccessEvaluation of deoxypyridinoline levels in gingival crevicular fluid and serum as alveolar bone loss biomarker in patients with periodontitis
Author(s) -
Suhail Syed,
Vinathi Reddy Kankara,
Krishnanjeya Reddy Pathakota,
Preethi Krishnan,
Ashank Mishra
Publication year - 2020
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/jisp.jisp_256_19
Subject(s) - medicine , deoxypyridinoline , dental alveolus , chronic periodontitis , periodontitis , biomarker , periodontology , dentistry , clinical attachment loss , gastroenterology , aggressive periodontitis , osteocalcin , biochemistry , chemistry , alkaline phosphatase , enzyme
Several components of gingival crevicular fluid (GCF) reflect the course and predictability of periodontal disease and provide a pointer toward disease status. Potential biomarkers deoxypyridinoline (DPD), a metallophosphoesterase would correctly determine the presence of osteoclast-mediated bone turnover activity and seems to hold great promise as a predictive marker to determine bone destruction and active phases in the disease progression.