Evaluation of deoxypyridinoline levels in gingival crevicular fluid and serum as alveolar bone loss biomarker in patients with periodontitis | Zendy

VinathiReddy Kankara | Zendy; Suhail Syed | Zendy; KrishnanjeyaReddy Pathakota | Zendy; Preethi Krishnan | Zendy; Ashank Mishra | Zendy

Open Access

Evaluation of deoxypyridinoline levels in gingival crevicular fluid and serum as alveolar bone loss biomarker in patients with periodontitis

Author(s) -

VinathiReddy Kankara,

Suhail Syed,

KrishnanjeyaReddy Pathakota,

Preethi Krishnan,

Ashank Mishra

Publication year - 2020

Publication title -

journal of indian society of periodontology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.309

H-Index - 28

eISSN - 0975-1580

pISSN - 0972-124X

DOI - 10.4103/jisp.jisp_256_19

Subject(s) - medicine , deoxypyridinoline , dental alveolus , chronic periodontitis , periodontitis , biomarker , periodontology , dentistry , clinical attachment loss , gastroenterology , aggressive periodontitis , osteocalcin , biochemistry , chemistry , alkaline phosphatase , enzyme

Several components of gingival crevicular fluid (GCF) reflect the course and predictability of periodontal disease and provide a pointer toward disease status. Potential biomarkers deoxypyridinoline (DPD), a metallophosphoesterase would correctly determine the presence of osteoclast-mediated bone turnover activity and seems to hold great promise as a predictive marker to determine bone destruction and active phases in the disease progression.

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