Evaluation and comparison of Vitamin D receptors in periodontal ligament tissue of Vitamin D-deficient chronic periodontitis patients before and after supplementation of Vitamin D3 | Zendy

VishakhaSarang Patil | Zendy; RohiniSalil Mali | Zendy; AlpanaSubodh Moghe | Zendy

Open Access

Evaluation and comparison of Vitamin D receptors in periodontal ligament tissue of Vitamin D-deficient chronic periodontitis patients before and after supplementation of Vitamin D3

Author(s) -

VishakhaSarang Patil,

RohiniSalil Mali,

AlpanaSubodh Moghe

Publication year - 2019

Publication title -

journal of indian society of periodontology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.309

H-Index - 28

eISSN - 0975-1580

pISSN - 0972-124X

DOI - 10.4103/jisp.jisp_173_18

Subject(s) - calcitriol receptor , vitamin d and neurology , medicine , periodontal fiber , chronic periodontitis , vitamin , periodontitis , vitamin d deficiency , endocrinology , receptor , cholecalciferol , calcitriol , dentistry

Vitamin D, an important hormone required by the body, exerts its biological effects through Vitamin D receptors (VDRs) present on target cells. Vitamin D is ineffective in tissues which lack VDR. Various tissues show the presence of VDRs. However, evidence for the presence of VDRs in human periodontal ligament tissue in fully erupted teeth in adults is lacking. The present study intends to evaluate the presence of VDRs in periodontal ligament (PDL) tissue and assess their response to serum Vitamin D3 levels in chronic periodontic patients.

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