Open AccessThe role of the combination of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (xenograft) as tooth extraction socket preservation materials on osteocalcin and transforming growth factor-beta 1 expressions in alveolar bone of Cavia cobaya
Author(s) -
Utari Kresnoadi,
Primanda Nur Rahmania,
Hera Utami Caesar,
Eha Djulaeha,
Bambang Agustono,
Muhammad Dimas Aditya Ari
Publication year - 2019
Publication title -
the journal of indian prosthodontic society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.419
H-Index - 20
eISSN - 1998-4057
pISSN - 0972-4052
DOI - 10.4103/jips.jips_251_18
Subject(s) - osteocalcin , moringa , dental alveolus , transforming growth factor , chemistry , dentistry , andrology , medicine , alkaline phosphatase , traditional medicine , biochemistry , enzyme
Alveolar bone resorption, often occurring after tooth extraction, can be minimized through socket preservation. This process uses a combination of Moringa leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) that is expected to generate both transforming growth factor-beta 1 (TGF-β1) expressions as a transcription factor associated with osteoblast differentiation and osteocalcin accelerating alveolar bone formation. This research aimed to analyze the role of the combination of Moringa leaf extract and DFDBBX induced in socket preservation when generating TGF-β1 and osteocalcin expressions.