Open AccessPerianal and perineal spindle cell variant of embryonal rhabdomyosarcoma in an infant
Author(s) -
Aditya Singh,
Kalpana Mangal,
Ramesh Tanger,
Arun Kumar Gupta,
M.Y. Ansari,
Arvind Kumar Shukla
Publication year - 2019
Publication title -
journal of indian association of pediatric surgeons
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.306
H-Index - 17
eISSN - 1998-3891
pISSN - 0971-9261
DOI - 10.4103/jiaps.jiaps_115_18
Subject(s) - embryonal rhabdomyosarcoma , myogenin , vimentin , medicine , immunohistochemistry , rhabdomyosarcoma , desmin , pathology , anatomy , biopsy , sarcoma , myogenesis , skeletal muscle
We present a case of a perianal and perianal spindle cell variant of embryonal rhabdomyosarcoma (RMS). A 3-month-old male child presented with a firm mass in the perianal region. The mass measured 5 cm × 3 cm × 2 cm was surgically removed. Biopsy was performed; it showed embryonal RMS. Immunohistochemical (IHC) stains were performed using vimentin, myogenin, spinal muscular atrophy, and muscle-specific actin, which all showed positive results. The histological examination and IHC stains were consistent with a spindle cell variant of embryonal RMS.