Open AccessRole of urinary transforming growth factor beta-b1 and monocyte chemotactic protein-1 as prognostic biomarkers in posterior urethral valve
Author(s) -
Pranay Panigrahi,
Sarita Chowdhary,
Seema Sharma,
Rakesh Kumar,
Neeraj Agarwal,
Seema Sharma
Publication year - 2020
Publication title -
journal of indian association of pediatric surgeons
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.306
H-Index - 17
eISSN - 1998-3891
pISSN - 0971-9261
DOI - 10.4103/jiaps.jiaps_104_19
Subject(s) - medicine , urinary system , posterior urethral valve , urology , urine , cystoscopy , biomarker , ablation , prospective cohort study , renal pelvis , surgery , biochemistry , chemistry
Posterior Urethral Valves (PUV) are the most common cause of congenital LUT obstruction in males. Biomarkers of glomerular or tubular injury may be of particular value in predicting the need for surgical intervention or in tracing progression of chronic kidney disease. Measurement of biomarker in urine is relatively easy.