Open AccessIndia's first successful surrogate birth after percutaneous oocyte retrieval following modified radical hysterectomy and right ovarian transposition to the anterior abdominal wall
Author(s) -
Priya Selvaraj,
Kamala Selvaraj,
Chitrathara Gangadharan,
Vijaya Annigeri,
Kalaichelvi Srinivasan,
Mahalakshmi Sivakumar
Publication year - 2019
Publication title -
journal of human reproductive sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 31
eISSN - 0974-1208
pISSN - 1998-4766
DOI - 10.4103/jhrs.jhrs_53_19
Subject(s) - medicine , gynecology , percutaneous , pregnancy , polycystic ovary , ovary , oocyte , ovarian hyperstimulation syndrome , in vitro fertilisation , obstetrics , surgery , embryo , biology , genetics , microbiology and biotechnology , insulin resistance , insulin
A 31-year-old woman, who is a known case of polycystic ovary syndrome, underwent modified radical hysterectomy and right ovarian transposition to the anterior abdominal wall for endometrioid adenocarcinoma Grade II. She then visited our facility for in vitro fertilization (IVF) and surrogacy in the year 2016. Three cycles of IVF were performed using gonadotropin-releasing hormone (GnRH) antagonist in the first two attempts and GnRH agonist in the third attempt, with percutaneous technique of oocyte retrieval from the transpositioned right ovary. In the third attempt in July 2017, we were able to retrieve five oocytes and subsequently froze three embryos and one blastocyst. The surrogate underwent sequential transfer in June 2018 which resulted in a positive clinical singleton pregnancy. The outcome of IVF following percutaneous oocyte retrieval led to a successful pregnancy and subsequent delivery by emergency cesarean by a healthy female baby on February 16, 2019. This is the first reported case of ovarian hyperstimulation and percutaneous aspiration of oocytes from a transpositioned right ovary (subcutaneous plane) in our country. Global literature survey revealed publications only of transabdominal retrieval of ovaries moved above the pelvic brim.