Open AccessThe correlation of chronological age and micro ribonucleic acid-135b expression in spent culture media of In vitro fertilisation patient
Author(s) -
Tiara Berliana Azzahra,
Ririn Rahmala Febri,
Pritta Ameilia Iffanolida,
Kresna Mutia,
Budi Wiweko
Publication year - 2022
Publication title -
journal of human reproductive sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 31
eISSN - 0974-1208
pISSN - 1998-4766
DOI - 10.4103/jhrs.jhrs_122_21
Subject(s) - microrna , biomarker , in vitro fertilisation , andrology , biology , embryo , medicine , genetics , gene
The lack of accuracy in embryo viability assessment methods still remains a challenge to increase the in vitro fertilisation (IVF) success rate. The chronological age and micro ribonucleic acid (RNA)-135b influence the quality of the embryo since microRNA-135b expresses stably in the spent culture media. Therefore, microRNA-135b has the potential to become a non-invasive biomarker of IVF embryo quality.