Open AccessBalanced reciprocal translocation: Multiple chromosome rearrangements in an infertile female
Author(s) -
Neelam Gupta,
Rupa Dalvi,
Neeraja Koppaka,
Swarna Mandava
Publication year - 2019
Publication title -
journal of human reproductive sciences
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 31
eISSN - 0974-1208
pISSN - 1998-4766
DOI - 10.4103/jhrs.jhrs_122_18
Subject(s) - chromosomal translocation , reciprocal , karyotype , biology , genetics , chromosome , chromosomal rearrangement , gene , philosophy , linguistics
Double reciprocal translocations and triple-balanced reciprocal translocations multiple chromosome rearrangements are very rare events in the phenotypically normal individuals. Chromosome analysis with 500-band resolution was performed and analyzed in an infertile woman. Her karyotype revealed 46,XX, t(1;3) (q44;p11), t(2;14) (q11.2;q13), t(9;11) (p22;p15) pattern in all the metaphases. To the best of our knowledge, this is the first case of triple-balanced reciprocal translocations in an infertile woman.