Open AccessMitochondrial DNA levels in trophectodermal cells show no association with blastocyst development and pregnancy outcomes
Author(s) -
G Ritu,
Geetha Veerasigamani,
M. Ashraf,
Sankalp Singh,
Saniya Laheri,
Stacy Colaco,
Deepak Modi
Publication year - 2022
Publication title -
journal of human reproductive sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 31
eISSN - 0974-1208
pISSN - 1998-4766
DOI - 10.4103/jhrs.jhrs_103_21
Subject(s) - blastocyst , mitochondrial dna , biology , miscarriage , aneuploidy , andrology , live birth , pregnancy , genetics , gynecology , medicine , embryo , embryogenesis , chromosome , gene
In patients undergoing assisted reproduction, levels of mitochondrial DNA (mtDNA) in the trophectodermal cells of the developing blastocyst are suggested to be associated with its ability to implant. However, discrepancies exist regarding the use of mtDNA levels as a reliable biomarker to predict outcomes of assisted reproduction.