Open AccessPott disease in a 14-year-old girl affected by congenital lamellar ichthyosis type 3 and diabetes mellitus
Author(s) -
Maria Elena Cucuzza,
Flavia La Mendola,
Angela D’Ambra,
Pierluigi Smilari,
Filippo Greco,
Agata Fiumara,
Andrea D. Praticò
Publication year - 2018
Publication title -
journal of global infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 25
eISSN - 0974-8245
pISSN - 0974-777X
DOI - 10.4103/jgid.jgid_82_17
Subject(s) - medicine , lamellar ichthyosis , dermatology , surgery , pediatrics , type 1 diabetes , ichthyosis , diabetes mellitus , endocrinology
Extrapulmonary manifestations of tuberculosis (TB) are particularly frequent during childhood, and usually involve the lymph nodes and the skull. They are related to predisposing immunosuppression conditions. A patient affected by diabetes mellitus type 1 (DMT1) and congenital lamellar ichthyosis type 3 came at our attention with a 4-year history of recurrent parotitis and severe back pain and inferior limb hypomobility, which had lasted for 6 months. A diagnosis of chronic TB parotitis combined with Pott disease was performed after a suggestive spinal magnetic resonance imaging, and positive culture and polymerase-chain reaction examination. Surgical aspiration of the fluid collection and a 12-month antitubercular treatment resulted in complete resolution of the symptomatology. This is the first report of a Pott disease in a patient affected by the two co-occurrences of two immunosuppression diseases such as DMT1 and congenital lamellar ichthyosis type 3.