Open AccessThe role of biochemical variations and genotype testing in determining the virological response of patients infected with hepatitis C virus
Author(s) -
Abid Shoukat,
Mosin Saleem Khan,
Syed Mudassar,
Zaffar Kawoosa,
Altaf Shah,
Showkat Ali Zargar
Publication year - 2018
Publication title -
journal of global infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 25
eISSN - 0974-8245
pISSN - 0974-777X
DOI - 10.4103/jgid.jgid_48_17
Subject(s) - ribavirin , medicine , pegylated interferon , viral load , interleukin 28b , hepatitis c virus , gastroenterology , genotype , immunology , alanine transaminase , hepatitis c , virology , biology , virus , gene , biochemistry
In hepatitis C virus (HCV), infection viral and IL28B genotype along with many clinical and biochemical factors can influence response rates to pegylated interferon plus ribavirin (Peg-IFN-a/R) therapy and progression to chronic hepatitis C (CHC).