Open AccessEarly results of fecal microbial transplantation protocol implementation at a community-based university hospital
Author(s) -
Rodrigo Duarte-Chavez,
Thomas R Wojda,
Thomas B. Zanders,
Berhanu Geme,
Gloria Fioravanti,
Stanislaw P. Stawicki
Publication year - 2018
Publication title -
journal of global infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 25
eISSN - 0974-8245
pISSN - 0974-777X
DOI - 10.4103/jgid.jgid_145_17
Subject(s) - medicine , clostridium difficile , discontinuation , colonoscopy , transplantation , antibiotics , infection control , concomitant , surgery , colorectal cancer , cancer , microbiology and biotechnology , biology
Clostridium difficile (CD) is a serious and increasingly prevalent healthcare-associated infection. The pathogenesis of CD infection (CDI) involves the acquisition of CD with a concurrent disruption of the native gut flora. Antibiotics are a major risk although other contributing factors have also been identified. Clinical management combines discontinuation of the offending antibiotic, initiation of CD-specific antibiotic therapy, probiotic agent use, fecal microbiota transplantation (FMT), and surgery as the "last resort" option. The aim of this study is to review short-term clinical results following the implementation of FMT protocol (FMTP) at our community-based university hospital.