Open AccessAction of colloidal bismuth hydroxide gel and its commercial cream on enteropathogens and colonizers of the gastrointestinal tract
Author(s) -
Tomás Subils,
Cecilia Casabonne,
Agustina González,
Virginia Aquili,
Claudia Balagué
Publication year - 2018
Publication title -
journal of global infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 25
eISSN - 0974-8245
pISSN - 0974-777X
DOI - 10.4103/jgid.jgid_102_17
Subject(s) - microbiology and biotechnology , antimicrobial , active ingredient , minimum inhibitory concentration , minimum bactericidal concentration , shigella flexneri , chemistry , bacterial growth , bismuth , escherichia coli , medicine , bacteria , biology , pharmacology , biochemistry , organic chemistry , genetics , gene
Acute diarrheal diseases constitute a world public health problem because they are the second cause of death in children under 5 years of age. Colloidal bismuth hydroxide gel (CBHG) is an active ingredient in low-cost, antidiarrhetic drugs for oral use; it does not inhibit intestinal motility, and it features very low intestinal absorption of <1%.