Open AccessRecurrent empty follicle syndrome with different stimulation protocols – A case report
Author(s) -
Athula Kaluarachchi,
Harshalal R. Seneviratne,
Tuan Milhan Batcha,
Sumedha Wijeratne,
Gardie Role Malwattage Udara Ganthika Peiris Jayawardena
Publication year - 2019
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/jfmpc.jfmpc_418_19
Subject(s) - medicine , human chorionic gonadotropin , infertility , gynecology , follicle , pregnancy , embryo transfer , oocyte , gonadotropin , ovary , stimulation , andrology , obstetrics , embryo , hormone , biology , genetics , microbiology and biotechnology
We report a case of recurrent empty follicle syndrome (EFS) where no oocytes were aspirated in two separate IVF cycles using two different protocols. In the second cycle, oocyte aspiration in one ovary was delayed for 24 hours after administering a second dose of human chorionic gonadotropin injection (hCG) and still no oocytes were recovered. In view of the presence of severe male factor infertility and failure to retrieve oocytes in 2 stimulated cycles, the couple was offered donor embryo transfer which resulted in a singleton pregnancy. A baby girl weighing 2800 g was delivered by an elective caesarean section at term. This case highlights that the change of protocol or repeat hCG administration is unlikely to change the outcome of genuine empty follicle syndrome.