Open AccessH-FABP: A beacon of hope for prediabetic heart disease
Author(s) -
Priyamvadha Ramesh,
Abha Chauhan,
Parul Goyal,
Akanksha Singh
Publication year - 2020
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/jfmpc.jfmpc_296_20
Subject(s) - medicine , prediabetes , context (archaeology) , diabetes mellitus , insulin resistance , mann–whitney u test , cardiology , gastroenterology , endocrinology , type 2 diabetes , obesity , paleontology , biology
Prediabetes is increasingly being studied in the context of its association with cardiovascular disease (CVD). Besides raised HbA1c and sugar levels, the major underlying defect seems to be insulin resistance (IR). Subclinical atherosclerosis, measured by high sensitivity C reactive protein (hsCRP) and carotid artery intima media thickness (CIMT) underlies the pathogenesis of CVD in prediabetes. Heart-type fatty acid binding protein (H-FABP), a novel cardiac biomarker also might have a role in predictin prediabetic heart disease.