Open AccessLinezolid-induced dental hyperpigmentation in an adult male being treated for an ulcer caused by atypical mycobacteria
Author(s) -
Prabhat Agrawal,
Prashant Prakash,
Nikhil Pursnani,
Maaz Farooqui
Publication year - 2018
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/jfmpc.jfmpc_284_18
Subject(s) - medicine , linezolid , hyperpigmentation , dermatology , antibiotics , mycobacterium , clarithromycin , dentistry , antimicrobial , surgery , pathology , microbiology and biotechnology , staphylococcus aureus , helicobacter pylori , bacteria , tuberculosis , vancomycin , biology , genetics
Mycobacteria are intrinsically resistant to most antibiotics as a result of multiple mechanisms. Linezolid, a member of the oxazolidinones, is a newer class of synthetic antimicrobials which is frequently used to treat mycobacteria. Here, we report a case of a patient with an ulcer on the right arm, caused by atypical mycobacteria, who presented with discoloration of both the upper and lower teeth after being treated with linezolid for a period of 2 months. On detailed evaluation, the patient was found to have linezolid-induced dental hyperpigmentation. This is the first case reported ever in an adult having linezolid-induced dental hyperpigmentation.