Open Access7.5% NaCl Resuscitation Leads to Abnormal Clot Fibrinolysis after Severe Hemorrhagic Shock and its Correction with 7.5% NaCl Adenosine, Lidocaine, and Mg2+
Author(s) -
Hayley L. Letson,
Geoffrey P. Dobson
Publication year - 2018
Publication title -
journal of emergencies, trauma and shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.313
H-Index - 29
eISSN - 0974-519X
pISSN - 0974-2700
DOI - 10.4103/jets.jets_84_17
Subject(s) - fibrinolysis , hyperfibrinolysis , thromboelastometry , medicine , anesthesia , resuscitation , shock (circulatory) , fibrin , platelet , immunology
Hyperfibrinolysis is a common complication of hemorrhagic shock. Our aim was to examine the effect of small-volume 7.5% NaCl adenosine, lidocaine, and Mg 2+ (ALM) on fibrinolysis in the rat model of hemorrhagic shock.