Open AccessDoes addition of postmastectomy radiotherapy improve outcome of patients with pT1-2, N0 triple negative breast cancer as compared to breast conservation therapy?
Author(s) -
Rajeev Kavalakara Raghavan,
Shabna Ibrahim,
K M Jagathnath Krishna,
Beela Sarah Mathew
Publication year - 2019
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_974_17
Subject(s) - medicine , lymphovascular invasion , stage (stratigraphy) , radiation therapy , breast cancer , mastectomy , triple negative breast cancer , oncology , modified radical mastectomy , surgical margin , breast conserving surgery , cancer , surgery , metastasis , paleontology , biology
Triple-negative breast cancers (TNBCs) form a heterogeneous group of cancers typically exhibiting an aggressive behavior resulting in increased risk of locoregional relapse (LRR) and distant metastases. The effect of radiotherapy on LRR risk and overall survival (OS) in women treated with mastectomy alone for early-stage TNBC remains unclear.