Open AccessImprovement of dose distribution in ocular brachytherapy with 125I seeds 20-mm COMS plaque followed to loading of choroidal tumor by gold nanoparticles
Author(s) -
Mansour Zabihzadeh,
Hadi Rezaee,
Seyed Mohammad Hosseini,
Mostafa Feghhi,
Amir Danyaei,
Mojtaba HoseiniGhahfarokhi
Publication year - 2019
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_907_17
Subject(s) - brachytherapy , sclera , choroidal melanoma , ocular melanoma , colloidal gold , nuclear medicine , melanoma , biomedical engineering , materials science , nanoparticle , medicine , radiation therapy , ophthalmology , radiology , cancer research , nanotechnology
Brachytherapy using removable ophthalmic plaques loaded with suitable small sealed radioactive seeds adjacent to the ocular's tumor has been widely used as an effective treatment. The aim of this study was to investigate the dose distribution in a modeled eyeball followed to loading of an ocular melanoma tumor with different concentrations of gold nanoparticles (GNPs) as dose enhancement agent by Monte Carlo (MC) calculations.