Open AccessCan consolidative thoracic radiotherapy improve outcomes in extensive-disease small cell lung cancer after chemotherapy with complete/near-complete responders?
Author(s) -
Esra Korkmaz Kıraklı,
Hasan Taylan Yılmaz,
Cimen Akcay,
Berna Kömürcüoğlu,
Ufuk Yılmaz
Publication year - 2020
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_776_17
Subject(s) - medicine , radiation therapy , lung cancer , prophylactic cranial irradiation , chemotherapy , progression free survival , radiology , magnetic resonance imaging , oncology , surgery , myocardial infarction , conventional pci
In extensive-disease-small cell lung cancer (ED-SCLC), the median survival is 8-10 months and 2-year survival is <5%. Primary tumor progression occurs in 90% of patients approximately within 1 year. The role of consolidative thoracic radiotherapy (C-TRT) for the postchemotherapy residue with the aim of improving local control (LC) and survival is currently of great interest. The objective of this study is to determine the effectiveness of C-TRT on LC, progression-free survival (PFS), and overall survival (OS) in ED-SCLC.