Open AccessA pilot study of the impact of Vitamin C supplementation with neoadjuvant chemoradiation on regulators of inflammation and carcinogenesis in esophageal cancer patients
Author(s) -
Mohamed Abdel-Latif,
Mahwash Babar,
Dermot Kelleher,
John V. Reynolds
Publication year - 2019
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_763_16
Subject(s) - medicine , inflammation , esophageal cancer , carcinogenesis , adenocarcinoma , vitamin c , vitamin , gastroenterology , cancer , proinflammatory cytokine , oncology
Vitamin C plays a role in chemoprevention in cancer treatment, and Vitamin C modulates many regulators of inflammation in in vitro studies. The aim of this study is to assess the effect of Vitamin C supplementation with neoadjuvant chemoradiation in esophageal adenocarcinoma on the nuclear factor-kappa B (NF-κB) and associated cytokines.