Open AccessExpression and clinical significance of centrosomal protein 55 in T-cell lymphoma
Author(s) -
Yangyang Xu,
Xiangxiang Zhou,
Ying Li,
Zhang Ya,
Xin Wang
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_758_17
Subject(s) - viability assay , cancer research , flow cytometry , cytokinesis , apoptosis , exact test , biology , medicine , cell , immunology , cell division , genetics
T-cell lymphomas (TCLs) have been heterogeneous lymphoid malignancies with aggressive clinical phenotype and poor prognosis. Centrosomal protein 55 (CEP55) played a critical role in cytokinesis and served as a centrosome- and midbody-associated protein. Previous studies have reported the overexpression and clinical significance of CEP55 in various human malignancies, but the exact biological roles of CEP55 in TCLs remained unclear.