Open AccessDetection of epidermal growth factor receptor mutation in the peripheral blood of patients with esophageal carcinoma to guide epidermal growth factor receptor-tyrosine kinase inhibitor treatment
Author(s) -
Yang Xu,
Zhihui Xie,
Hong Lü
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_735_17
Subject(s) - gefitinib , epidermal growth factor receptor , mutation , medicine , cancer research , tyrosine kinase inhibitor , carcinoma , epidermal growth factor , exon , tyrosine kinase , esophageal cancer , pathology , oncology , gastroenterology , cancer , biology , receptor , gene , genetics
This study aimed to explore the epidermal growth factor receptor (EGFR) mutation in the peripheral blood of patients with esophageal carcinoma and analyze the relationship between EGFR-tyrosine kinase inhibitor (EGFR-TKI) therapeutic effect and EGFR mutation in peripheral blood.