Open Access7-geranyloxycoumarin enhanced radiotherapy effects on human gastric adenocarcinoma cells
Author(s) -
FatemehB Rassouli,
Jebrail Movaffagh,
Hamide Salari,
Elahe Merajifar,
Hamid Gholamhosseinian,
Azadeh Shahroodi,
Mehrdad Iranshahi
Publication year - 2021
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_701_21
Subject(s) - propidium iodide , viability assay , apoptosis , annexin , flow cytometry , cytotoxicity , cancer research , chemistry , cisplatin , pharmacology , biology , microbiology and biotechnology , in vitro , programmed cell death , biochemistry , chemotherapy , genetics
Gastric adenocarcinoma (GA) is a serious malignancy with growing incidence and mortality rate worldwide. The objective of the present study was to determine whether 7-geranyloxycoumarin, a natural monoterpene coumarin, could induce anticancer effects, in single use and/or in combination with anticancer drugs and ionizing radiation, on GA cells.