Open AccessHuman herpes virus-8-negative kaposiform sarcoma in a HIV-positive male: Novel variant
Author(s) -
Pratap Kumar
Publication year - 2020
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_62_17
Subject(s) - sarcoma , immunohistochemistry , kaposi's sarcoma , pathology , human immunodeficiency virus (hiv) , medicine , virus , herpes virus , virology , human herpesvirus
Human herpes virus (HHV)-8 is associated with causation of Kaposi's sarcoma (KS). An HIV-positive male with multiple nodules on the body was clinically and histopathologically diagnosed as a case of KS; however, immunohistochemistry was negative for HHV-8. This peculiar scenario of HHV-8-negative tumor with typical clinical and histopathologic findings was labeled as "Atypical spindled endothelial proliferation suspicious of Kaposi sarcoma", hitherto unreported novel entity.