Open AccessGnathic variant of primary adenoid cystic carcinoma
Author(s) -
Sayani Shome,
Aishika Mallick,
S. S. Kundu,
Swagata Gayen
Publication year - 2022
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_56_20
Subject(s) - adenoid cystic carcinoma , medicine , perineural invasion , stage (stratigraphy) , radiological weapon , distant metastasis , carcinoma , radiology , pathology , metastasis , cancer , paleontology , biology
Adenoid Cystic Carcinoma (AdCC) is an uncommon malignant epithelial salivary gland neoplasm, which is indolent yet persistent. Intraosseous /central variant of AdCC of the jaw is poorly understood owing to its innocuous clinical presentation thus posing a diagnostic challenge. AdCC is characterized by perineural invasion, late distant metastasis and a high recurrence rate , thus having a major effect on the mortality and morbidity rate. It is often diagnosed at an advanced stage which is chiefly achieved through histological examination and complete clinic-radiological work up. A clinical case of an intraosseous variant of AdCC, involving the mandible of a 49 year old male patient is discussed herewith, encompassing the entire spectrum of clinicopathological, radiological and treatment modalities rendered.